Since everyone else is establishing their expected plot lines, I'll layout my reasoning for what I expect is likely to happen.
First, I believe the end result is that the Genin team will succeed in returning Sasuke to Konoha. Reasoning: the manga has an established theme that Naruto, through strength, determination and spirit, keeps his promises. He promised himself early on that he would change, and not run from danger: he stood up to Zabuza. He promised he would beat Neji after the defeat of Hinata. Despite odds, he did so. He told Tsunade that he WOULD learn the rasengan, and did so. Now, he's promised Sakura that he would bring back Sasuke. Somehow, he will manage it--likely, though, Sasuke will be more angsty inside, and have the power of the 2nd level seal.
Second, based on the current progression of fighting, one genin will square off with the 3rd Sound. It was already established that Kidoumaru is the strongest of the 4 Sound Nins, so it is feasible that the 3rd could be beaten. Who knows which one it will be. However, that will leave one Sound Nin to continue along with Sasuke, and two genins. I expect Naruto to be present when Sasuke emerges from the protective seal. In fact, my expectation, even from the Chouji fight, is that all five of the genin will converge together after having defeated the four Sound Nins. A Whether there is a Naruto v. Sasuke fight, I don't know. Sasuke may feel that he has been "recognized" by the effort of the genins. He may feel that the 2nd level of the seal is the power he needed from Orochimaru. Or perhaps something none of us have considered will be the winning notion to return Sasuke. Orochimaru himself fears the effect Naruto has had on Sasuke, in terms of drawing him away from the desire for revenge.
It is also my expectation, based on Kishimoto's story telling style, that the genins are not going to die, even Neji and Chouji. Though some of you have expressed distaste for them, they are overall popular characters, and it does not make sense to kill off your main cast! Kishimoto has written about his strong admiration for the Dragonball series (one of his inspirations for becoming a mangaka), and may mimic some of the style of taking characters to their extremes, but somehow they manage to survive. I do not have any idea how Kishimoto plans to pull that off though. We've already seen how long it's taken for Rock Lee to recover from his injuries.
Personally, I just continue to be excited for the forthcoming chapters!