Man, I just had the craziest of ideas: Okay, so Orochimaru was sealed away by Itachi. And we assumed that even though Kabuto carried Orochimaruīs DNA, this would at most result in Kabuto being a bit "like" Oro, but not turn him into the actual Oro. Well, didnīt Kishimoto set up a precedence for the opposite to be true? When Sandaime sealed away just Orochimaruīs arms in their battle on the roof top in Konoha, we thought that would be the end for them. Well, turns out that a new body was enough to somehow restore his soul. I think thatīs enough evidence to at least consider the possibility of Orochimaru coming back into the world by having his DNA grow on Kabutoīs body, thus restoring Oroīs soul, as established by his own experiments.

Not saying that it will happen, only that it could happen.