I think this anime pretty much is telling us Ohana is the successor to the inn...
She's familly
She's able to have people following her ideas and most of the time good ones at that
She loves the place
She only needs experience.
Okami-san being only in her late 60's, she might live long enough to train Ohana into the head of Kissuisso for at least 5 if not 10 years.
Just my 2 cents.