The Naruto story has one very enduring constant: strength trumps all. It trumps experience, it trumps inventiveness, cleverness, it trumps numbers, everything. If there's a significant strength difference between opponents, the weaker opponent certainly cannot beat the stronger, but he also cannot hide from the stronger, cannot run from the stronger, cannot outsmart the stronger to any significant effect. The only time variables other than strength matter, is when the opponents are evenly matched in strength. There used to be this rock/paper/scissors theory going around about which fighter would be able to defeat which other fighter, but clearly that's been done away by a preponderance of evidence against that theory found in the manga. Strength far outweighs all else.

Right now, it's kind of difficult to gauge what Sasuke's strength is. He's been able to use, time and time again, his ultimate eye techniques. In fact, they were his most used techniques since the start of the fight against the kages. Kakashi, died trying to use his mangekyo less than a handful of times. I'm with everyone that if Sasuke is that strong, it's complete BS. Unfortunately, that would be perfectly in line with the manga. I don't want to see Kakashi lose, but I would not be surprised either way.