Depends who i`m facing, usually i don`t harrass at all and focus on farming, then the enemy gets used on not being harrassed and i do a qweq combo (preferably after i get tear), that should do decent amount of damage, then i flash in and exhaust and do my full combo (qeqwq), enemy will flash out but they`ll be exhausted, you should be able to reach them.
If i dont think i can harrass at all then i just play safe all lane and focus on those tear stacks, Ryze`s early lane is his weakest.