I actually think that Juugo will stand up against it. I mean he is the source of the of Curse Seal. What if he could actually go to level 3 and become all huge like that. Sure it would be kinda lame but I think that it could happen. And then Sasuke will go like: Hmm maybe I can do that too" And then it will turn out he can too because of what Juugo did to him by healing him.

I know its rather far-fetched but you'll never know with Kishi at the moment =\