So I'm in act 1 on nightmare with a level 33 monk.
This is my grind setup:
http://us.battle.net/d3/en/calculato...ifQ!cbX!aZZZZa
This is my power setup:
http://us.battle.net/d3/en/calculato...djQ!cbX!ZZaZZa
One thing I especially love to do with the grind setup is combine cyclone with lashing tail or wave of light to alternate drawing enemies into me and knocking them away.
I also have some heavy vitality buffs on my gear, too. I think my monk has like 3600 hitpoints right now.